Quantitative Methods for HIV Researchers: Workshop Series

HIV/AIDS research is generating increasingly large and complex data sets. To analyze these data sets, we need the next generation of HIV/AIDS researchers to learn skills in data processing and statistical analysis, as well as increase collaboration with quantitative scientists such as statisticians, mathematicians, computer scientists and engineers. The curriculum will train HIV/AIDS researchers in the data science and statistics skills required to analyze multi-parameter data through a series of hands-on workshops

2025 – 2026 Workshop Series: Quantitative Methods for HIV Researchers

Register HERE by Monday, September 22, 2025

Overview

The Quantitative Methods for HIV/AIDS workshop series is designed to provide HIV researchers with a hands-on introduction to quantitative analyses both through simple and large, complex data sets. These NIH-funded workshops are open to graduate students, postdocs, medical fellows, staff, and faculty working in the HIV/AIDS field. Non-Duke-affiliated applicants are welcome.

Details

Each part of the series consists of six, virtual, once-a-week workshops held on Mondays from 1 – 4 PM through Zoom. 

  • Part I workshops will teach reproducible research and R language skills along with an introduction to data analysis and study design. The seminars will be taught using RStudio. (Note: R knowledge is necessary for Part II- Statistics Workshops and Part III- Assay Analysis Workshops).
    • There will be a Day 0: Introduction to R seminar for those with no prior experience in R. Participants with R experience may skip this session, but are welcome to attend.
  • Part II workshops will build on the statistical concepts discussed in Part 1 and the utilization of predictive models using previously published HIV data. Attendees will learn important concepts in statistics and perform statistical analyses using real HIV data. We will introduce hypothesis testing, multiple testing correction, linear and logistic regression, and high dimensional modeling. The final day is scheduled as a design studio where participants can sign up to discuss their work and receive feedback from instructors and fellow workshop attendees
  • Part III workshops will teach bioinformatics skills for analysis of high throughput sequencing datasets.

NOTE: The material presented in Part I is a pre-requisite for Part II and Part III. Participants fluent with R, RStudio, and Git may skip the Part I Workshops, but must understand that the material covered in Part I will not be reviewed in Part II and Part III. Part I seminars will be recorded for attendees unable to attend Part I but interested in Parts II/III. Priority registration will be given to those who attended the previous parts.

2025 – 2026 Workshops Schedule

Part I: Data Science Workshops

9/29/2025       Introduction to R (*not a required workshop)

10/6/2025       Intro to Data Driven Research, Part 1

10/20/2025     Intro to Data Driven Research, Part 2

10/27/2025     Exploratory analysis and visualization, Part 1

11/3/2025       Exploratory analysis and visualization, Part 2

11/10/2025      Exploratory analysis and visualization, Part 3

11/17/2025      Case Study Walk-through

 

Part II: Statistical Thinking Workshops

January - February 2026      TBD

 

Part III: Assays Workshops

March - April 2026                 TBD

PART I: Data Science Workshops (must commit to attend all 6 sessions)

Monday, Oct 7 Introduction to R (not required) Overview of general usage of R Link to Workshop Recording
Monday, Oct 21 Intro to Data Driven Research, Part 1 Discussion of Reproducible Research Link to Workshop Recording
Monday, Oct 28 Intro to Data Driven Research, Part 2 The use of Tidyr and dplyr Link to Workshop Recording
Monday, Nov 4 Exploratory analysis and visualization, Part 1 Visualizations with Base R and ggplot2 graphics Link to Workshop Recording
Monday, Nov 11 Exploratory analysis and visualization, Part 2 The Scientific Process, common data types, calculating summary statistics and graphical summaries Link to Workshop Recording
Monday, Nov 18 Exploratory analysis and visualization, Part 3 Probability Distributions. Sampling and QQ plots. Confidence intervals Link to Workshop Recording
Monday, Nov 25 Case Study Walk-through Case Study Walk-through Link to Workshop Recording

 

PART II: Statistical Thinking Workshops

Date Workshop Description Workshop Recording
Monday, Jan 27, 2025 Hypotheses, non-parametric tests, power, and error Link
Monday, Feb 3, 2025 Linear regression, categorical predictors, interaction effect Link
Monday, Feb 10, 2025 Logistic regression and classification Link
Monday, Feb 17, 2025 Penalized regression, cross-validation, overfitting Link
Monday, Feb 24, 2025 Random forest, principal component regression Link
Monday, March 3, 2025 Data Workshop Link

 

PART III: Bioinformatics Workshops (must commit to attend all 6 sessions)

Date Workshop Description Location Time
Monday, March 10, 2025 Introduction to High-throughput sequencing Watch on YouTube 1pm - 4pm
Monday, March 17, 2025 Bioinformatics for RNA-seq Watch on YouTube 9am - Noon
Monday, March 24, 2025 Bioinformatics for scRNA-seq Watch on YouTube 1pm - 4pm
Monday, March 31, 2025 Statistical Analysis for RNA-seq Zoom 1pm - 4pm
Monday, April 7, 2025 scRNA-Seq: Overview of tools; Using Seurat for QC, Transformations, and Normalization Zoom 1pm - 4pm
Monday, April 14, 2025 scRNA-Seq: Dimension reduction, Clustering, Cluster Annotation, Visualization, and Pseudo-bulking Zoom 1pm - 4pm