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New insight on potent HIV antibody could improve vaccine design

Wednesday, February 20, 2019

DURHAM, N.C. - In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of antibodies are able to dock and neutralize the virus.

But true to form with HIV, these broadly neutralizing antibodies, or bnAbs, are highly complex and arise under an intricate series of events that have been difficult to trace backward to their origins and recreate.

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