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HIV Prevention: A B

The Overbaugh lab has a long-standing interest in understanding the mechanisms of HIV-1 transmission and pathogenesis. Previously, the lab has shown that there is a genetic bottleneck in the viruses that are transmitted between heterosexual partners, leading to selection of just one or a few HIV variants in the new host. Members of the lab have also found similar evidence of a bottleneck in the context of mother-infant transmission, where the infant is infected in the presence of maternal HIV-specific antibodies. Current work aims to reveal how the transmitted variants "escape" from maternal immune pressure and elucidate whether functional characteristics of maternal antibodies from the blood and breast milk compartments are associated with risk of transmission.

Please see the flyer for more information.

 

Start Date
Friday, April 22, 2016
End Date
Friday, April 22, 2016
Start Time
2:00 pm
Location
143 Jones Bldg