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Longitudinal Data Analysis of a Group-Based Mental Health Intervention for Adolescents Living With HIV in Tanzania

Longitudinal Data Analysis of a Group-Based Mental Health Intervention for Adolescents Living With HIV in Tanzania

Adolescents living with HIV have worse antiretroviral therapy adherence and virology outcomes compared to children or adults. Inadequate adherence has been statistically associated with self-reported high levels of stigma and mental health difficulties. This project enrolled adolescents living with HIV in Tanzania to be randomized to either the group-based mental health intervention, Sauti ya Vijana (The Voice of Youth), or treatment as usual (NCT02888288). The database consists of demographics, mental health measures (PHQ9, SDQ, UCLA trauma RI), truncated Berger’s Stigma scale, self-reported antiretroviral therapy (ART) adherence questions (Wilsons, 3 questions), and additional risk questions about sex, disclosure, and substance use. Quantitative measures of adherence include ART drug concentration in hair samples, viral loads, and possibly resistance data if funding is secured. Data is longitudinal with time points pre-intervention, 6, 12, and 24-months post intervention. Youth received the intervention in 3 waves (~40 each wave) and the first wave will complete 24-month follow-up by Jan 2019. The control group is in the process of cross over to intervention; therefore, analyses for change are between treatment arms and within treatment arm.

The mentee will work closely with statisticians John Gallis and Liz Turner who are currently on the project.