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FcR Genotypes

FcR Genotypes

As part of our D- AIDS-funded P01, we are genotyping Fc receptors in humans and rhesus macaques. The diversity in macaques is greater than in humans, and there is no clear map between human and rhesus FcRs that can predict function or outcomes. We have obtained a large number of samples for which there is outcomes data and are in the process of sequencing them, with the goal of determining whether any genotype is associated with greater or lesser protection. The project would involve manipulating the datasets and investigating this question in a systematic fashion.