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Structural Biology of HIV-1 entry

Structural Biology of HIV-1 entry

  • HIV/- AIDS mentor: Priyamvada Acharya (, Director, Division of Structural Biology, Duke Human Vaccine Institute (DHVI)

The Division of Structural Biology at the DHVI uses a number of complementary approaches to study HIV-1 entry. These include structural techniques, such as cryo-electron microscopy (cryo-EM) and X-ray crystallography, and surface plasmon resonance (SPR) to measure biomolecular interactions, and complements these with biological assays including measurements of virus entry into cells, to decipher the mechanism of HIV-1 entry into cells.  This project will involve comprehensive analyses of available data with the aim of creating tools for visualization of HIV-1 entry into cells.

Special Features

  • Opportunity to be involved in structural biology projects- both x-ray crystallography and cryo-EM – within a collaborative environment.