Structural Biology of HIV-1 entry
- HIV/- AIDS mentor: Priyamvada Acharya (firstname.lastname@example.org), Director, Division of Structural Biology, Duke Human Vaccine Institute (DHVI)
The Division of Structural Biology at the DHVI uses a number of complementary approaches to study HIV-1 entry. These include structural techniques, such as cryo-electron microscopy (cryo-EM) and X-ray crystallography, and surface plasmon resonance (SPR) to measure biomolecular interactions, and complements these with biological assays including measurements of virus entry into cells, to decipher the mechanism of HIV-1 entry into cells. This project will involve comprehensive analyses of available data with the aim of creating tools for visualization of HIV-1 entry into cells.
- Opportunity to be involved in structural biology projects- both x-ray crystallography and cryo-EM – within a collaborative environment.