The overall Organizational Structure of the Duke CFAR consists of seven individual Cores that serve a total of five broad Research Programs. The Duke CFAR seeks to recruit and retain the very best basic and clinical investigators to perform cutting edge, state-of-the-art research that will have the greatest possible impact on the development of innovative new preventive and therapeutic strategies to control and ultimately eradicate HIV infection. The Duke CFAR also seeks to reach out to intramural scientists who are not presently involved in AIDS-related research, but whose research talents and interests could greatly compliment and extend the scope of ongoing or future investigations.  An equally important mission of the Duke CFAR is its central role and important commitment to the comprehensive training and mentoring of young basic and clinical scientists who represent the next generation of scientific investigators and who will become the leaders in shaping the course of future medical research over the next 25 years and beyond.